ARG65188

anti-CD305 / LAIR1 antibody

anti-CD305 / LAIR1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Immune System antibody

概述

产品描述 Goat Polyclonal antibody recognizes CD305 / LAIR1
反应物种 Hu
应用 IHC-P, WB
特异性 This antibody is expected to recognize both isoforms (NP_002278.1; NP_068352.1).
宿主 Goat
克隆 Polyclonal
同位型 IgG
靶点名称 CD305 / LAIR1
抗原物种 Human
抗原 C-NDTEDVSQASPSE
偶联标记 Un-conjugated
別名 LAIR-1; hLAIR1; CD305; CD antigen CD305; Leukocyte-associated immunoglobulin-like receptor 1

应用说明

应用建议
应用 推荐稀释比
IHC-P3 - 5 µg/ml
WB1 - 3 µg/ml
应用说明 WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Purified from goat serum by antigen affinity chromatography.
缓冲液 Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 0.5% BSA
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 3903 Human LAIR1

Swiss-port # Q6GTX8 Human Leukocyte-associated immunoglobulin-like receptor 1

背景介绍 The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. [provided by RefSeq, Jul 2008]
研究领域 Immune System antibody
预测分子量 31 kDa
翻译后修饰 Phosphorylation at Tyr-251 and Tyr-281 activates it. May be phosphorylated by LCK.
N-glycosylated.

检测图片 (2) Click the Picture to Zoom In

  • ARG65188 anti-CD305 / LAIR1 antibody WB image

    Western blot: Human Lymph Node lysate (35 µg protein in RIPA buffer) stained with ARG65188 anti-CD305 / LAIR1 antibody at 2 µg/ml dilution.

  • ARG65188 anti-CD305 / LAIR1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human tonsil tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG65188 anti-CD305 / LAIR1 antibody at 3.75 µg/ml dilution followed by AP-staining.