ARG65552
anti-CD300e antibody [UP-H2]
anti-CD300e antibody [UP-H2] for Flow cytometry,Functional study,Immunoprecipitation,Western blot and Human
Immune System antibody
概述
| 产品描述 | Mouse Monoclonal antibody [UP-H2] recognizes CD300e |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, FuncSt, IP, WB |
| 特异性 | The clone UP-H2 recognizes CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | UP-H2 |
| 同位型 | IgG1 |
| 靶点名称 | CD300e |
| 抗原 | CD300e-HA-transfected cells |
| 偶联标记 | Un-conjugated |
| 別名 | Poly-Ig receptor 2; Immune receptor expressed on myeloid cells 2; IREM-2; CD300LE; CMRF35-A5; CD antigen CD300e; CLM2; IREM2; CMRF35-like molecule 2; PIgR2; CLM-2; Polymeric immunoglobulin receptor 2; PIgR-2; CD300 antigen-like family member E |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | Functional studies: Stimulation. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from hybridoma culture supernatant by protein-A affinity chromatography. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide |
| 抗菌剂 | 15 mM Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CD300E |
| 全名 | CD300e molecule |
| 背景介绍 | CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers. |
| 生物功能 | Probably acts as an activating receptor. [UniProt] |
| 研究领域 | Immune System antibody |
| 预测分子量 | 23 kDa |
| 翻译后修饰 | N-glycosylated. |
克隆号文献
Molecular characterization of a novel immune receptor restricted to the monocytic lineage.
