ARG66206
anti-CD21 antibody [SQab1728]
anti-CD21 antibody [SQab1728] for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections and Human
参考文献1
概述
| 产品描述 | Recombinant Rabbit Monoclonal antibody [SQab1728] recognizes CD21 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, IHC-P |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | SQab1728 |
| 同位型 | IgG |
| 靶点名称 | CD21 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the C‐terminus of CD21. |
| 偶联标记 | Un-conjugated |
| 別名 | Cr2; Complement C3d receptor; C3DR; CD21; CD antigen CD21; Complement receptor type 2; SLEB9; CR; CVID7; Epstein-Barr virus receptor; EBV receptor |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CR2 |
| 全名 | complement component (3d/Epstein Barr virus) receptor 2 |
| 背景介绍 | This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] |
| 生物功能 | Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation. [UniProt] |
| 产品亮点 | Related products: CD21 antibodies; CD21 ELISA Kits; Related news: Cancer Pathology Markers (SQ clones) |
| 预测分子量 | 113 kDa |
检测图片 (4) Click the Picture to Zoom In
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ARG66206 anti-CD21 antibody [SQab1728] IHC-P image
Immunohistochemistry: Human tissue samples are from PD-1 myopathy stained with ARG66206 anti-CD21 antibody [SQab1728].
From Matsubara S et al. J Immunother Cancer- (2019), doi: 10.1186/s40425-019-0736-4, Fig. 4.
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ARG66206 anti-CD21 antibody [SQab1728] FACS image
Flow Cytometry: Ramos cells were fixed with 4% paraformaldehyde (10 min) and then permeabilized with 0.1% TritonX-100 for 15 min. The cells were then stained with ARG66206 anti-CD21 antibody [SQab1728] (red) at 1:10 dilution in 1x PBS/1% BSA for 30 min at room temperture, followed by Alexa Fluor® 488 labelled secondary antibody. Unlabelled sample (black) was used as a control.
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ARG66206 anti-CD21 antibody [SQab1728] IHC-P image
Immunohistochemistry: Formalin‐fixed and paraffin‐embedded Human spleen tissue stained with ARG66206 anti-CD21 antibody [SQab1728] at 1:200 dilution.
Antigen retrieval: Heat mediated was performed using Tris/EDTA buffer pH 9.0
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ARG66206 anti-CD21 antibody [SQab1728] IHC-P image
Immunohistochemistry: Formalin‐fixed and paraffin‐embedded Human appendix tissue stained with ARG66206 anti-CD21 antibody [SQab1728] at 1:200 dilution.
Antigen retrieval: Heat mediated was performed using Tris/EDTA buffer pH 9.0
文献引用
Tertiary lymphoid organs in the inflammatory myopathy associated with PD-1 inhibitors.
IHC-P / Human
