ARG22907
anti-CD21 antibody [LB21]
anti-CD21 antibody [LB21] for Flow cytometry,IHC-Frozen sections,Immunoprecipitation and Human,Bovine,Cat,Goat,Sheep
概述
| 产品描述 | Mouse Monoclonal antibody [LB21] recognizes CD21 Mouse anti Human CD21 antibody, clone LB21 recognizes the human Complement receptor type 2, also known as CD21 or the Epstein-Barr virus receptor. CD21 is a ~14 kDa cell surface glycoprotein expressed by mature B cells and by follicular dendritic cells. The molecule acts as a receptor for complement components C3d, C3dg and iC3b, as well as for Epstein Barr Virus. It forms part of a large signal transduction complex in association with CD19. |
|---|---|
| 反应物种 | Hu, Bov, Cat, Goat, Sheep |
| 应用 | FACS, IHC-Fr, IP |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | LB21 |
| 同位型 | IgG1 |
| 靶点名称 | CD21 |
| 抗原物种 | Human |
| 抗原 | Human IM9 cell line. |
| 偶联标记 | Un-conjugated |
| 別名 | Cr2; Complement C3d receptor; C3DR; CD21; CD antigen CD21; Complement receptor type 2; SLEB9; CR; CVID7; Epstein-Barr virus receptor; EBV receptor |
应用说明
| 应用建议 |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-Fr: The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. Arigo recommends the use of acetone fixation for frozen sections. FACS: Use 10 µl of the suggested working dilution to label 10^6 cells or 100 µl human whole blood. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified by ion exchange chromatography. |
| 缓冲液 | PBS, 0.09% Sodium azide and 1% BSA |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 1% BSA |
| 浓度 | 25 µg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CR2 |
| 全名 | complement component (3d/Epstein Barr virus) receptor 2 |
| 背景介绍 | This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] |
| 生物功能 | Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation. [UniProt] |
| 预测分子量 | 113 kDa |
检测图片 (11) Click the Picture to Zoom In
-
ARG22907 anti-CD21 antibody [LB21] FACS image
Flow Cytometry: Human peripheral blood lymphocytes stained with ARG22907 anti-CD21 antibody [LB21].
-
ARG22907 anti-CD21 antibody [LB21] IHC-Fr image
Immunohistochemistry: Human tonsil cryosection stained with Sheep anti Human LOX-1 antibody (red) and ARG22907 anti-CD21 antibody [LB21] (green). Nuclei are stained blue using DAPI. Merged image on right.
-
ARG22907 anti-CD21 antibody [LB21] IHC-Fr image
Immunohistochemistry: Human tonsil cryosection stained with Mouse anti Human CD1a antibody, red in A and ARG22907 anti-CD21 antibody [LB21], green in B. C is the merged image with nuclei counterstained blue using DAPI. (High power).
-
ARG22907 anti-CD21 antibody [LB21] IHC-Fr image
Immunohistochemistry: Human spleen cryosection stained with ARG22907 anti-CD21 antibody [LB21]. (Low power).
-
ARG22907 anti-CD21 antibody [LB21] IHC-Fr image
Immunohistochemistry: Human spleen cryosection stained with ARG22907 anti-CD21 antibody [LB21]. (High power).
-
ARG22907 anti-CD21 antibody [LB21] IHC-Fr image
Immunohistochemistry: Human tonsil cryosection stained with ARG22907 anti-CD21 antibody [LB21]. (Medium power).
-
ARG22907 anti-CD21 antibody [LB21] IHC-Fr image
Immunohistochemistry: Human tonsil cryosection stained with ARG22907 anti-CD21 antibody [LB21]. (Medium power).
-
ARG22907 anti-CD21 antibody [LB21] IHC-Fr image
Immunohistochemistry: Human tonsil cryosection stained with ARG22907 anti-CD21 antibody [LB21]. (High power).
-
ARG22907 anti-CD21 antibody [LB21] IHC-Fr image
Immunohistochemistry: Human tonsil cryosection stained with Mouse anti Human CD11b antibody, clone ICRF44, red in A and ARG22907 anti-CD21 antibody [LB21], green in B. C is the merged image with nuclei counterstained blue using DAPI. (Medium power).
-
ARG22907 anti-CD21 antibody [LB21] IHC-Fr image
Immunohistochemistry: Human tonsil cryostection stained with Mouse anti Human CD83 antibody, clone HB15e, red in A and ARG22907 anti-CD21 antibody [LB21], green in B. The merged image is in C with nuclei counterstained blue using DAPI. (Low power).
-
ARG22907 anti-CD21 antibody [LB21] IHC-Fr image
Immunohistochemistry: Human tonsil cryostection stained with Mouse anti Human CD83 antibody, clone HB15e, red in A and ARG22907 anti-CD21 antibody [LB21], green in B. The merged image is in C with nuclei counterstained blue using DAPI. (High power).
