ARG22651
anti-CD21 antibody [CA2.1D6]
anti-CD21 antibody [CA2.1D6] for Flow cytometry,IHC-Frozen sections,Immunoprecipitation and Cat,Dog,Horse
概述
| 产品描述 | Mouse Monoclonal antibody [CA2.1D6] recognizes CD21 This antibody recognizes Canine CD21, also known as Complement receptor type 2. CD21is a cell surface antigen expressed by Canine B lymphocytes. The antigen recognised may be the Canine homologue of Human CD21, but this has not been fully confirmed. Mouse anti Canine CD21 antibody , clone CA2.1D6 also recognizes the CD21 antigen in Felids. Expression in cats is analogous to that seen in dogs with strong expression on lymphocytes, in a manner mutually exclusive with expression of CD4 or CD8. Clone CA2.1D6 also immunoprecipitates a 145kDa protein from feline lymphocytes, similar to the protein immunoprecipitated by the antibody from Canine lymphocytes (Dean et al. 1996). |
|---|---|
| 反应物种 | Cat, Dog, Hrs |
| 应用 | FACS, IHC-Fr, IP |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | CA2.1D6 |
| 同位型 | IgG1 |
| 靶点名称 | CD21 |
| 抗原物种 | Dog |
| 偶联标记 | Un-conjugated |
| 別名 | Cr2; Complement C3d receptor; C3DR; CD21; CD antigen CD21; Complement receptor type 2; SLEB9; CR; CVID7; Epstein-Barr virus receptor; EBV receptor |
应用说明
| 应用建议 |
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| 应用说明 | FACS: Use 10 µl of the suggested working dilution to label 10^6 cells or 100 µl whole blood. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS and 0.09% Sodium azide. |
| 抗菌剂 | 0.09% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | CR2 |
|---|---|
| 全名 | complement component (3d/Epstein Barr virus) receptor 2 |
| 背景介绍 | This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] |
| 生物功能 | Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation. [UniProt] |
| 预测分子量 | 113 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG22651 anti-CD21 antibody [CA2.1D6] FACS image
Flow Cytometry: Canine peripheral blood lymphocytes stained with ARG22651 anti-CD21 antibody [CA2.1D6].
