ARG62403
anti-CD2 antibody [B336 (HuLy-m1)]
anti-CD2 antibody [B336 (HuLy-m1)] for Flow cytometry,IHC-Frozen sections and Human
Developmental Biology antibody; Immune System antibody
概述
| 产品描述 | Mouse Monoclonal antibody [B336 (HuLy-m1)] recognizes CD2 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, IHC-Fr |
| 特异性 | Reacts with the majority of T-cells in peripheral lymphoid tissue, cortical thymocytes, and most T-cell neoplasms. Also reacts with the E-rosette receptor on T-cells. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | B336 (HuLy-m1) |
| 同位型 | IgG2b |
| 靶点名称 | CD2 |
| 抗原物种 | Human |
| 抗原 | Human thymocytes (3 pooled donors) |
| 偶联标记 | Un-conjugated |
| 別名 | T-cell surface antigen T11/Leu-5; LFA-3 receptor; T-cell surface antigen CD2; SRBC; Erythrocyte receptor; CD antigen CD2; T11; Rosette receptor; LFA-2 |
应用说明
| 应用说明 | FACS: 1-5 mg/106 cells. IHC-Fr: 10-20 ug/mL. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | 1X PBS buffer with < 0.1% sodium azide. |
| 抗菌剂 | < 0.1% sodium azide. |
| 浓度 | 2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CD2 |
| 全名 | CD2 molecule |
| 背景介绍 | CD2 is a 50 kDa single-chain type I transmembrane glycoprotein, originally defined as the sheep erythrocyte receptor. CD2 is one of the earliest T-cell lineage-restricted antigens to appear during T-cell differentiation, and it is expressed on most thymocytes, peripheral T cells and NK cells. Originally identified as a sheep RBC receptor, functions as a CD58 receptor and mediates activation of T-cells, NK cells and dendritic cells. |
| 生物功能 | CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. [UniProt] |
| 研究领域 | Developmental Biology antibody; Immune System antibody |
| 预测分子量 | 39 kDa |
