ARG45724
anti-CD1d antibody
anti-CD1d antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
产品描述 | Rabbit Polyclonal antibody recognizes CD1d |
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反应物种 | Hu |
应用 | IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | CD1d |
抗原物种 | Human |
抗原 | Synthetic peptide corresponding to N-terminal region of human CD1d. |
偶联标记 | Un-conjugated |
別名 | CD1D; CD1d Molecule; Antigen-Presenting Glycoprotein CD1d; CD1D Antigen, D Polypeptide; CD1d Antigen; R3G1; HMC Class I Antigen-Like Glycoprotein CD1D; Differentiation Antigen CD1-Alpha-3; T-Cell Surface Glycoprotein CD1d; Thymocyte Antigen CD1D; CD1A; R3 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Affinity purified |
缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
抗菌剂 | 0.05% Thimerosal and 0.05% Sodium azide |
稳定剂 | 5% BSA |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 |
Swiss-port # P15813 Human Antigen-presenting glycoprotein CD1d |
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基因名称 | CD1D |
全名 | CD1d Molecule |
背景介绍 | This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016] |
生物功能 | Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells. [UniProt] |
细胞定位 | Cell membrane; Endoplasmic reticulum; Endosome; Lysosome; Membrane. [UniProt] |
预测分子量 | 38 kDa |
翻译后修饰 | Disulfide bond; Glycoprotein. [UniProt] |
检测图片 (2) Click the Picture to Zoom In