ARG53785
anti-CD1a antibody [HI149] (APC)
anti-CD1a antibody [HI149] (APC) for Flow cytometry and Human
Immune System antibody
概述
| 产品描述 | APC-conjugated Mouse Monoclonal antibody [HI149] recognizes CD1a |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS |
| 特异性 | The clone HI149 reacts with CD1a (T6), a 49 kDa polypeptide associated with beta2-microglobulin expressed on cortical thymocytes (strongly), Langerhans cells, dendritic cells and some T cell leukemias and lymphomas. does not react with peripheral blood T and B lymphocytes, monocytes, granulocytes, platelets and erythrocytes. HLDA V; WS Code CD01.01 |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | HI149 |
| 同位型 | IgG1 |
| 靶点名称 | CD1a |
| 抗原物种 | Human |
| 抗原 | Human thymocytes |
| 偶联标记 | APC |
| 別名 | R4; FCB6; CD antigen CD1a; T6; T-cell surface antigen T6/Leu-6; hTa1 thymocyte antigen; T-cell surface glycoprotein CD1a; CD1; HTA1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化说明 | The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary. |
| 缓冲液 | PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA |
| 抗菌剂 | 15 mM Sodium azide |
| 稳定剂 | 0.2% (w/v) high-grade protease free BSA |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CD1A |
| 全名 | CD1a molecule |
| 背景介绍 | CD1a, together with CD1b and c, belongs to group 1 of CD1 glycoproteins. These proteins serve as antigen-presenting molecules for a subset of T cells that responds to specific lipids and glycolipids found in the cell walls of bacterial pathogens or self-glycolipid antigens such as gangliosides, and they have also roles in antiviral immunity. Unlike CD1b, CD1a is excluded from late endosomal compartments and instead traffics independently in the recycling pathway of the early endocytic system, and CD1a antigen presentation is independent upon vesicular acidification. |
| 生物功能 | Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. [UniProt] |
| 产品亮点 | Related products: CD1a antibodies; Anti-Mouse IgG secondary antibodies; Related news: Detecting exosomal HMGB1 for ICD research |
| 研究领域 | Immune System antibody |
| 预测分子量 | 37 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG53785 anti-CD1a antibody [HI149] (APC) FACS image
Flow Cytometry: MOLT-4 cells (partially positive, red) and SP2 cells (negative, blue) stained with ARG53785 anti-CD1a antibody [HI149] (APC).
