ARG45112
anti-CD192 / CCR2 antibody
anti-CD192 / CCR2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Goat Polyclonal antibody recognizes CD192 / CCR2 |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, IHC-P |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CD192 / CCR2 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to N-terminus of Human CD192 / CCR2 protein. |
| 偶联标记 | Un-conjugated |
| 別名 | chemokine (C-C motif) receptor 2; HGNC:1603; CC-CKR-2; CCR2A; CCR2B; CKR2; CKR2A; CKR2B; CMKBR2; MCP-1-R; MCP-1 receptor; chemokine (C-C) receptor 2; monocyte chemoattractant protein 1 receptor; monocyte chemotactic protein 1 receptor |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CCR2 |
| 全名 | chemokine (C-C motif) receptor 2 |
| 背景介绍 | The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. [provided by RefSeq, Aug 2017] |
| 生物功能 | Receptor for the CCL2, CCL7 and CCL13 chemokines. Transduces a signal by increasing intracellular calcium ion levels. Alternative coreceptor with CD4 for HIV-1 infection. [UniProt] |
| 细胞定位 | Cell membrane [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG45112 anti-CD192 / CCR2 Antibody ICC/IF image
Immunofluorescence: THP-1 cells stained with ARG45112 anti-CD192 / CCR2 Antibody at 10μg/ml dilution.
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ARG45112 anti-CD192 / CCR2 Antibody IHC-P image
Immunohistochemistry: Human Tonsil stained with ARG45112 anti-CD192 / CCR2 Antibody at 6μg/ml dilution.
