ARG54231
anti-CD160 antibody [BY55] (PE)
anti-CD160 antibody [BY55] (PE) for Flow cytometry and Human
Immune System antibody
概述
| 产品描述 | PE-conjugated Mouse Monoclonal antibody [BY55] recognizes CD160 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS |
| 特异性 | The clone BY55 recognizes CD160, a 27 kDa glycoprotein expressed on NK cells, NK-T cells, intestinal intraepithelial lymphocytes, TCR-gamma/delta T cells and a small population of TCR-alpha/beta T cells. detects both GPI-anchored and transmembrane form of CD160. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | BY55 |
| 同位型 | IgM |
| 靶点名称 | CD160 |
| 抗原物种 | Human |
| 抗原 | Human NK cell line YT2C2 |
| 偶联标记 | PE |
| 別名 | BY55; Natural killer cell receptor BY55; NK28; NK1; CD antigen CD160; CD160 antigen |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化说明 | The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary. |
| 缓冲液 | TBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA |
| 抗菌剂 | 15 mM Sodium azide |
| 稳定剂 | 0.2% (w/v) high-grade protease free BSA |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CD160 |
| 全名 | CD160 molecule |
| 背景介绍 | CD160 is a cell surface glycoprotein of immunoglobulin superfamily, which functions as a costimulatory receptor expressed mainly on cytotoxic cell populations and recognizing both classical and non-classical MHC class I molecules. It can form disulfide-linked multimers. Down-modulation of CD160 occurs as a consequence of its proteolytic cleavage and the released soluble form was found to impair the MHC-class I specific cytotoxicity of CD8+ T lymphocytes and NK cells. In contrast to GPI-anchored isoform with broader expression among CD160 positive cells, expression of the transmembrane isoform is restricted to NK cells and is activation-dependent. |
| 生物功能 | Receptor showing broad specificity for both classical and non-classical MHC class I molecules. [UniProt] |
| 研究领域 | Immune System antibody |
| 预测分子量 | 20 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG54231 anti-CD160 antibody [BY55] (PE) FACS image
Flow Cytometry: Human peripheral whole blood stained with ARG54231 anti-CD160 antibody [BY55] (PE) (10 µl reagent / 100 µl of peripheral whole blood).
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ARG54231 anti-CD160 antibody [BY55] (PE) FACS image
Flow Cytometry: Human lymphocytes stained with ARG54231 anti-CD160 antibody [BY55] (PE) (10 µl reagent / 100 µl of peripheral whole blood) and ARG53782 anti-CD19 antibody [LT19] (APC) (10 µl reagent / 100 µl of peripheral whole blood).
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ARG54231 anti-CD160 antibody [BY55] (PE) FACS image
Flow Cytometry: Separation of human CD160 positive B cells (red-filled) from neutrophil granulocytes (black-dashed). Human peripheral whole blood stained with ARG54231 anti-CD160 antibody [BY55] (PE) (10 µl reagent / 100 µl of peripheral whole blood).
克隆号文献
A novel 80-kD cell surface structure identifies human circulating lymphocytes with natural killer activity.
