ARG23613
anti-CD150 / SLAM antibody [9D1] (PE)
anti-CD150 / SLAM antibody [9D1] (PE) for Flow cytometry and Mouse
概述
| 产品描述 | PE-conjugated Rat Monoclonal antibody [9D1] recognizes CD150 / SLAM. This product recognizes murine CD150, also known as signalling lymphocyte activation molecule (SLAM) . Murine CD150 is a 75 kDa cell surface glycoprotein that is expressed on T-cells and B-cells, and is upregulated on activated T-cells and stimulated macrophages. The extracellular domain of CD150 is the receptor for the measles virus (Erlenhoefer et al. 2001) and acts as a co-activator on T-cells and B-cells.Rat anti Mouse CD150 antibody, clone 9D1 has functional activity (Howie et al. 2002). |
|---|---|
| 反应物种 | Ms |
| 应用 | FACS |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | 9D1 |
| 同位型 | IgG1 |
| 靶点名称 | CD150 / SLAM |
| 抗原物种 | Mouse |
| 抗原 | CHO cells stably transfected with Mouse CD150. |
| 偶联标记 | PE |
| 別名 | Signaling lymphocytic activation molecule; IPO-3; CD150; SLAM; CDw150; CD antigen CD150 |
应用说明
| 应用建议 |
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| 应用说明 | FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS, 0.09% Sodium azide, 1% BSA and 5% Sucrose. |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 1% BSA and 5% Sucrose |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9QUM4 Mouse Signaling lymphocytic activation molecule |
|---|---|
| 基因名称 | SLAMF1 |
| 全名 | signaling lymphocytic activation molecule family member 1 |
| 生物功能 | High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates. [UniProt] |
| 预测分子量 | 37 kDa |
| 翻译后修饰 | Phosphorylated on tyrosine residues by FYN. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG23613 anti-CD150 / SLAM antibody [9D1] (PE) FACS image
Flow Cytometry: Mouse thymus cells stained with ARG23613 anti-CD150 / SLAM antibody [9D1] (PE).
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ARG23613 anti-CD150 / SLAM antibody [9D1] (PE) FACS image
Flow Cytometry: Figure A. PE-A750 tandem-conjugated Rat anti-Mouse CD45R and PE-conjugated Rat IgG1 isotype control. Figure B. PE-A750 tandem-conjugated Rat anti-Mouse CD45R and ARG23613 anti-CD150 / SLAM antibody [9D1] (PE). All experiments performed on Mouse splenocytes.
