ARG21333
anti-CD14 antibody [UCHM-1] (PE-Cyanine 5)
anti-CD14 antibody [UCHM-1] (PE-Cyanine 5) for Blocking,Depletion,Flow cytometry,ICC/IF,IHC-Frozen sections and Human
Developmental Biology antibody; Immune System antibody; General Lymphocyte Marker Study antibody; Macrophages and neutrophils antibody
概述
| 产品描述 | PE-Cyanine 5-conjugated Mouse Monoclonal antibody [UCHM-1] recognizes CD14 |
|---|---|
| 反应物种 | Hu |
| 应用 | BL, Depletion, FACS, ICC/IF, IHC-Fr |
| 特异性 | Human/Cynomolgus CD14. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | UCHM-1 |
| 同位型 | IgG2a, kappa |
| 靶点名称 | CD14 |
| 抗原物种 | Human |
| 抗原 | Thymocytes and peripheral blood lymphocytes from a remission AML patient |
| 偶联标记 | PE-Cyanine 5 |
| 別名 | CD antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; Monocyte differentiation antigen CD14 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | PBS, 0.1% Sodium azide and Sucrose. |
| 抗菌剂 | 0.1% Sodium azide |
| 稳定剂 | Sucrose |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P08571 Human Monocyte differentiation antigen CD14 |
|---|---|
| 基因名称 | CD14 |
| 全名 | CD14 molecule |
| 背景介绍 | The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Mar 2010] |
| 生物功能 | In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. [UniProt] |
| 研究领域 | Developmental Biology antibody; Immune System antibody; General Lymphocyte Marker Study antibody; Macrophages and neutrophils antibody |
| 预测分子量 | 40 kDa |
| 翻译后修饰 | N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan. |
检测图片 (1) Click the Picture to Zoom In
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ARG21333 anti-CD14 antibody [UCHM-1] (PE-Cyanine 5) FACS image
Flow Cytometry: Human peripheral blood monocytes and lymphocytes stained with ARG21333 anti-CD14 antibody [UCHM-1] (PE-Cyanine 5) and Mouse anti-Human CD3 antibody (PE).
