ARG55960
anti-CD11c antibody [HC1/1]
anti-CD11c antibody [HC1/1] for Flow cytometry,Functional study,ICC/IF and Human
概述
| 产品描述 | Mouse Monoclonal antibody [HC1/1] recognizes CD11c |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, FuncSt, ICC/IF |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | HC1/1 |
| 同位型 | IgG1, kappa |
| 靶点名称 | CD11c |
| 抗原物种 | Human |
| 抗原 | Human monocytic U937 phorbol ester-treated cells. |
| 偶联标记 | Un-conjugated |
| 別名 | CD antigen CD11c; Leu M5; CD11C; SLEB6; Integrin alpha-X; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; CD11 antigen-like family member C |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 0.1 mg/ml BSA |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ITGAX |
| 全名 | integrin, alpha X (complement component 3 receptor 4 subunit) |
| 背景介绍 | This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013] |
| 生物功能 | Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. [UniProt] |
| 细胞定位 | Cell surface |
| 预测分子量 | 128 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG55960 anti-CD11c antibody [HC1/1] FACS image
Flow Cytometry: Human PBMCs stained with ARG55960 anti-CD11c antibody [HC1/1] (red) and isotype control antibody (green).
