ARG21322

anti-CD11c antibody [3.9]

anti-CD11c antibody [3.9] for Flow cytometry,IHC-Frozen sections,Immunoprecipitation,Blocking and Human,Rhesus Monkey

概述

产品描述 Mouse Monoclonal antibody [3.9] recognizes CD11c
反应物种 Hu, R. Mk
应用 BL, FACS, IHC-Fr, IP
特异性 Human/Rhesus/Cynomolgus CD11c.
宿主 Mouse
克隆 Monoclonal
克隆号 3.9
同位型 IgG1κ
靶点名称 CD11c
抗原物种 Human
抗原 Rheumatoid synovial cells and human monocytes
偶联标记 Un-conjugated
全名 integrin, alpha X (complement component 3 receptor 4 subunit)
別名 CD antigen CD11c; Leu M5; CD11C; SLEB6; Integrin alpha-X; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; CD11 antigen-like family member C

应用说明

应用建议
应用 推荐稀释比
BLAssay-dependent
FACS< 1 µg/10^6 cells
IHC-FrAssay-dependent
IPAssay-dependent
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
缓冲液 BBS (pH 8.2)
浓度 0.1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 3687 Human ITGAX

Swiss-port # P20702 Human Integrin alpha-X

基因名称 ITGAX
基因全名 integrin, alpha X (complement component 3 receptor 4 subunit)
背景介绍 This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
生物功能 Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. [UniProt]