ARG42424
anti-CD109 antibody [W7C5] (PE)
anti-CD109 antibody [W7C5] (PE) for Flow cytometry and Human
概述
| 产品描述 | PE-conjugated Mouse Monoclonal antibody [W7C5] recognizes CD109 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS |
| 特异性 | The mouse monoclonal antibody W7C5 recognizes CD109, an approximately 165 kDa GPI-anchored extracellular protein expressed mainly on various hematopoietic cells, activated T lymphoblasts, activated platelets, and endothelial cells. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | W7C5 |
| 同位型 | IgG1 |
| 靶点名称 | CD109 |
| 抗原物种 | Human |
| 抗原 | WERI-Rb-1 retinoblastoma cell line. |
| 偶联标记 | PE |
| 別名 | p180; CPAMD7; Platelet-specific Gov antigen; CD109 antigen; r150; 150 kDa TGF-beta-1-binding protein; CD antigen CD109; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified |
| 缓冲液 | PBS and 15 mM Sodium azide. |
| 抗菌剂 | 15 mM Sodium azide |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CD109 |
| 全名 | CD109 molecule |
| 背景介绍 | This gene encodes a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014] |
| 生物功能 | Modulates negatively TGFB1 signaling in keratinocytes. [UniProt] |
| 细胞定位 | Cell membrane; Lipid-anchor, GPI-anchor. [UniProt] |
| 预测分子量 | 162 kDa |
| 翻译后修饰 | N-glycosylated. 2 forms of 150 (p150) and 120 kDa (p120) exist due to proteolytic degradation from a 180 kDa form. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG42424 anti-CD109 antibody [W7C5] (PE) FACS image
Flow Cytometry: Human PHA stimulated peripheral blood mononuclear cells stained with ARG42424 anti-CD109 antibody [W7C5] (PE) at 10 µl / 10^6 cells in 100 µl of cell suspension.
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ARG42424 anti-CD109 antibody [W7C5] (PE) FACS image
Flow Cytometry: Separation of Human CD109 positive cells (red-filled) from CD109 negative cells (black-dashed). Human PHA stimulated peripheral blood mononuclear cells stained with ARG42424 anti-CD109 antibody [W7C5] (PE) at 10 µl / 10^6 cells in 100 µl of cell suspension.
