ARG67012
anti-CD107b / LAMP2 antibody
anti-CD107b / LAMP2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
概述
| 产品描述 | Mouse Monoclonal antibody recognizes CD107b / LAMP2 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2a |
| 靶点名称 | CD107b / LAMP2 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein corresponding to a region of Human CD107b / LAMP2. |
| 偶联标记 | Un-conjugated |
| 別名 | CD antigen CD107b; LAMPB; CD107b; LGP110; Lysosome-associated membrane glycoprotein 2; LAMP-2; CD107 antigen-like family member B; Lysosome-associated membrane protein 2 |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen retrieval: Heat tissue section in Sodium citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 阳性对照 | HeLa | ||||||||
| 实际分子量 | 100-130 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.2) and 0.09% Sodium azide. |
| 抗菌剂 | 0.09% Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P13473 Human Lysosome-associated membrane glycoprotein 2 Swiss-port # P17047 Mouse Lysosome-associated membrane glycoprotein 2 |
|---|---|
| 基因名称 | LAMP2 |
| 全名 | lysosomal-associated membrane protein 2 |
| 背景介绍 | The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2008] |
| 生物功能 | Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens. [UniProt] |
| 预测分子量 | 45 kDa |
| 翻译后修饰 | O- and N-glycosylated; some of the 16 N-linked glycans are polylactosaminoglycans. |
检测图片 (2) Click the Picture to Zoom In
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ARG67012 anti-CD107b / LAMP2 antibody WB image
Western blot: 50 µg of HeLa cell lysate stained with ARG67012 anti-CD107b / LAMP2 antibody at 1:500 dilution, overnight at 4°C.
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ARG67012 anti-CD107b / LAMP2 antibody FACS image
Flow Cytometry: Human KG1 cells stained with ARG67012 anti-CD107b / LAMP2 antibody at 1:50 dilution (grey area).
