ARG57348
anti-CCT4 / TCP1 delta antibody
anti-CCT4 / TCP1 delta antibody for ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CCT4 / TCP1 delta |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CCT4 / TCP1 delta |
| 抗原物种 | Human |
| 抗原 | Recombinant Protein of Human CCT4 / TCP1 delta. |
| 偶联标记 | Un-conjugated |
| 別名 | SRB; T-complex protein 1 subunit delta; CCT-DELTA; CCT-delta; Stimulator of TAR RNA-binding; TCP-1-delta; Cctd |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | THP-1 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CCT4 |
| 全名 | chaperonin containing TCP1, subunit 4 (delta) |
| 背景介绍 | The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).[supplied by OMIM, Mar 2008] |
| 生物功能 | Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin. [UniProt] |
| 预测分子量 | 58 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG57348 anti-CCT4 / TCP1 delta antibody ICC/IF image
Immunofluorescence: HeLa cells stained with ARG57348 anti-CCT4 / TCP1 delta antibody.
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ARG57348 anti-CCT4 / TCP1 delta antibody WB image
Western blot: THP-1 cell lysate stained with ARG57348 anti-CCT4 / TCP1 delta antibody.
