ARG45339
anti-CCRL-2 antibody [5A15]
anti-CCRL-2 antibody [5A15] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Mouse Monoclonal antibody [5A15] recognizes CCRL-2 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 5A15 |
| 同位型 | IgG2 |
| 靶点名称 | CCRL-2 |
| 抗原物种 | Human |
| 抗原 | Recombinant Human CCRL-2. |
| 偶联标记 | Un-conjugated |
| 別名 | CCRL2; C-C Motif Chemokine Receptor Like 2; CKRX; HCR; CRAM-B; CRAM-A; ACKR5; Chemokine (C-C Motif) Receptor-Like 2; Putative MCP-1 Chemokine Receptor; Atypical Chemokine Receptor 5; C-C Chemokine Receptor-Like 2; Chemokine Receptor CCR11; Chemokine Receptor X; CRAM; CCR11; CCR6 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein G chromatography |
| 缓冲液 | PBS |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CCRL2 |
| 全名 | C-C Motif Chemokine Receptor Like 2 |
| 背景介绍 | This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located. [provided by RefSeq, Jul 2008] |
| 生物功能 | Receptor for CCL19 and chemerin/RARRES2. Does not appear to be a signaling receptor, but may have a role in modulating chemokine-triggered immune responses by capturing and internalizing CCL19 or by presenting RARRES2 ligand to CMKLR1, a functional signaling receptors. Plays a critical role for the development of Th2 responses. [UniProt] |
| 细胞定位 | Cell membrane; Membrane. [UniProt] |
| 预测分子量 | 40 kDa |
| 翻译后修饰 | Disulfide bond; Glycoprotein. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG45339 anti-CCRL-2 antibody [5A15] IHC-P image
Immunohistochemistry: Human placental stained with ARG45339 anti-CCRL-2 antibody [5A15].
