ARG66092

anti-CCL4 / MIP1 beta antibody

anti-CCL4 / MIP1 beta antibody for ELISA,Neutralizing,Western blot and Mouse

概述

产品描述 Rabbit Polyclonal antibody recognizes CCL4 / MIP1 beta
反应物种 Ms
应用 ELISA, Neut, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 CCL4 / MIP1 beta
抗原物种 Mouse
抗原 E. coli derived recombinant Mouse CCL4 / MIP1 beta.
(APMGSDPPTS CCFSYTSRQL HRSFVMDYYE TSSLCSKPAV VFLTKRGRQI CANPSEPWVT EYMSDLELN)
偶联标记 Un-conjugated
別名 ACT2; G-26; HC21; LAG1; LAG-1; MIP1B; SCYA2; SCYA4; MIP1B1; AT744.1; MIP-1-beta

应用说明

应用建议
应用 推荐稀释比
ELISASandwich: 0.5 - 2.0 µg/ml with ARG66093 as a detection antibody
Neut8.0 - 10.0 µg/ml (To yield [ND50] of the biological activity of Murine MIP-1β (100.0 ng/ml) )
WB0.1 - 0.2 µg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 PBS (pH 7.2)
浓度 1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 20303 Mouse CCL4

Swiss-port # P14097 Mouse C-C motif chemokine 4

基因名称 Ccl4
全名 chemokine (C-C motif) ligand 4
背景介绍 The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. [provided by RefSeq, Dec 2012]
生物功能 Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. [UniProt]
预测分子量 10 kDa

检测图片 (3) Click the Picture to Zoom In

  • ARG66092 anti-CCL4 / MIP1 beta antibody WB image

    Western blot: 250 - 0.24 ng of Mouse MIP-1β stained with ARG66092 anti-CCL4 / MIP1 beta antibody, under non-reducing conditions.

  • ARG66092 anti-CCL4 / MIP1 beta antibody standard curve image

    Sandwich ELISA: ARG66092 anti-CCL4 / MIP1 beta antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with ARG66093 anti-CCL4 / MCP1 beta antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density reading at 405 - 650 nm.

  • ARG66092 anti-CCL4 / MIP1 beta antibody WB image

    Western blot: 250 - 0.24 ng of Mouse MIP-1β stained with ARG66092 anti-CCL4 / MIP1 beta antibody, under reducing conditions.