ARG56759
anti-CCL3 / MIP1 alpha antibody (Biotin)
anti-CCL3 / MIP1 alpha antibody (Biotin) for ELISA,Western blot and Rat
概述
| 产品描述 | Biotin-conjugated Rabbit Polyclonal antibody recognizes CCL3 / MIP1 alpha |
|---|---|
| 反应物种 | Rat |
| 应用 | ELISA, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CCL3 / MIP1 alpha |
| 抗原物种 | Rat |
| 抗原 | E.coli derived Recombinant Rat MIP-1α (CCL3). (APYGADTPTA CCFSYGRQIP RKFIADYFET SSLCSQPGVI FLTKRNRQIC ADPKETWVQE YITELELNA) |
| 偶联标记 | Biotin |
| 別名 | MIP-1-alpha; SIS-beta; PAT 464.1; Tonsillar lymphocyte LD78 alpha protein; G0/G1 switch regulatory protein 19-1; Small-inducible cytokine A3; C-C motif chemokine 3; LD78-alpha; 4-69; Macrophage inflammatory protein 1-alpha; MIP1A; SCYA3; G0S19-1; LD78ALPHA |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified by affinity chromatography. |
| 缓冲液 | PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | Ccl3 |
| 全名 | chemokine (C-C motif) ligand 3 |
| 背景介绍 | This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.[provided by RefSeq, Sep 2010] |
| 生物功能 | Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). [UniProt] |
| 预测分子量 | 10 kDa |
| 翻译后修饰 | N-terminal processed form LD78-alpha(4-69) is produced by proteolytic cleavage after secretion from HTLV1-transformed T-cells. |
检测图片 (1) Click the Picture to Zoom In
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ARG56759 anti-CCL3 / MIP1 alpha antibody (Biotin) standard curve image
Sandwich ELISA: ARG56759 anti-CCL3 / MIP1 alpha antibody (Biotin) as a detection antibody at 0.25 - 1.0 µg/ml combined with ARG56650 anti-MIP1 alpha / CCL3 antibody as a capture antibody. Results of a typical standard run with optical density.
