ARG56649

anti-CCL3 / MIP1 alpha antibody

anti-CCL3 / MIP1 alpha antibody for ELISA,Western blot and Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes CCL3 / MIP1 alpha
反应物种 Ms, Rat
应用 ELISA, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 CCL3 / MIP1 alpha
抗原物种 Mouse
抗原 E.coli derived Recombinant Mouse MIP-1α (CCL3).
(APYGADTPTA CCFSYSRKIP RQFIVDYFET SSLCSQPGVI FLTKRNRQIC ADSKETWVQE YITDLELNA)
偶联标记 Un-conjugated
別名 MIP-1-alpha; SIS-beta; PAT 464.1; Tonsillar lymphocyte LD78 alpha protein; G0/G1 switch regulatory protein 19-1; Small-inducible cytokine A3; C-C motif chemokine 3; LD78-alpha; 4-69; Macrophage inflammatory protein 1-alpha; MIP1A; SCYA3; G0S19-1; LD78ALPHA

应用说明

应用建议
应用 推荐稀释比
ELISASandwich: 0.5 - 2.0 µg/ml with ARG56760 as a detection antibody
WB0.1 - 0.2 µg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 PBS (pH 7.2)
浓度 1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 20302 Mouse CCL3

GeneID: 25542 Rat CCL3

Swiss-port # P10855 Mouse C-C motif chemokine 3

Swiss-port # P50229 Rat C-C motif chemokine 3

基因名称 Ccl3
全名 chemokine (C-C motif) ligand 3
背景介绍 This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.[provided by RefSeq, Sep 2010]
生物功能 Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). [UniProt]
预测分子量 10 kDa
翻译后修饰 N-terminal processed form LD78-alpha(4-69) is produced by proteolytic cleavage after secretion from HTLV1-transformed T-cells.

检测图片 (3) Click the Picture to Zoom In

  • ARG56649 anti-CCL3 / MIP1 alpha antibody WB image

    Western blot: 250 - 0.24 ng of Mouse MIP-1α stained with ARG56649 anti-CCL3 / MIP1 alpha antibody, under reducing conditions.

  • ARG56649 anti-CCL3 / MIP1 alpha antibody WB image

    Western blot: 250 - 0.24 ng of Mouse MIP-1α stained with ARG56649 anti-CCL3 / MIP1 alpha antibody, under non-reducing conditions.

  • ARG56649 anti-CCL3 / MIP1 alpha antibody standard curve image

    Sandwich ELISA: ARG56649 anti-CCL3 / MIP1 alpha antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with ARG56760 anti-MIP1 alpha / CCL3 antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density.