ARG10026
anti-CCL3 / MIP1 alpha antibody [199]
anti-CCL3 / MIP1 alpha antibody [199] for ELISA and Human
Immune System antibody
概述
| 产品描述 | Mouse Monoclonal antibody [199] recognizes CCL3 / MIP1 alpha |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | Does not show any cross reaction with other human cytokines or growth factors tested such as M-CSF, GM-CSF, IL-7, IL-8, IL-16, IL-1β, bFGF, TGF-β, EGF, TNF-α and EPO. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 199 |
| 同位型 | IgG2a, kappa |
| 靶点名称 | CCL3 / MIP1 alpha |
| 抗原物种 | Human |
| 抗原 | Purified recombinant human MIP-1α |
| 偶联标记 | Un-conjugated |
| 別名 | MIP-1-alpha; SIS-beta; PAT 464.1; Tonsillar lymphocyte LD78 alpha protein; G0/G1 switch regulatory protein 19-1; Small-inducible cytokine A3; C-C motif chemokine 3; LD78-alpha; 4-69; Macrophage inflammatory protein 1-alpha; MIP1A; SCYA3; G0S19-1; LD78ALPHA |
应用说明
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein G affinity purified |
| 缓冲液 | 0.01M PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CCL3 |
| 全名 | chemokine (C-C motif) ligand 3 |
| 背景介绍 | This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.[provided by RefSeq, Sep 2010] |
| 生物功能 | Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). [UniProt] |
| 研究领域 | Immune System antibody |
| 预测分子量 | 10 kDa |
| 翻译后修饰 | N-terminal processed form LD78-alpha(4-69) is produced by proteolytic cleavage after secretion from HTLV1-transformed T-cells. |
