ARG56757
anti-CCL22 / MDC antibody (Biotin)
anti-CCL22 / MDC antibody (Biotin) for ELISA,Western blot and Human
概述
| 产品描述 | Biotin-conjugated Rabbit Polyclonal antibody recognizes CCL22 / MDC |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CCL22 / MDC |
| 抗原物种 | Human |
| 抗原 | E.coli derived Recombinant Human MDC (CCL22). (GPYGANMEDS VCCRDYVRYR LPLRVVKHFY WTSDSCPRPG VVLLTFRDKE ICADPRVPWV KMILNKLSQ) |
| 偶联标记 | Biotin |
| 別名 | CC chemokine STCP-1; Stimulated T-cell chemotactic protein 1; 3-69; Macrophage-derived chemokine; MDC; DC/B-CK; SCYA22; Small-inducible cytokine A22; ABCD-1; 7-69; 1-69; A-152E5.1; STCP-1; 5-69; C-C motif chemokine 22 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified by affinity chromatography. |
| 缓冲液 | PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CCL22 |
| 全名 | chemokine (C-C motif) ligand 22 |
| 背景介绍 | This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. [provided by RefSeq, Sep 2014] |
| 生物功能 | May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active. [UniProt] |
| 预测分子量 | 11 kDa |
| 翻译后修饰 | The N-terminal processed forms MDC(3-69), MDC(5-69) and MDC(7-69) are produced by proteolytic cleavage after secretion from monocyte derived dendrocytes. |
检测图片 (4) Click the Picture to Zoom In
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ARG56757 anti-CCL22 / MDC antibody (Biotin) WB image
Western blot: 250 - 0.24 ng of Human MDC stained with ARG56757 anti-CCL22 / MDC antibody (Biotin), under reducing conditions.
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ARG56757 anti-CCL22 / MDC antibody (Biotin) standard curve image
Direct ELISA: ARG56757 anti-CCL22 / MDC antibody (Biotin) at 0.25 - 1.0 µg/ml results of a typical standard run with optical density.
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ARG56757 anti-CCL22 / MDC antibody (Biotin) WB image
Western blot: 250 - 0.24 ng of Human MDC stained with ARG56757 anti-CCL22 / MDC antibody (Biotin), under non-reducing conditions.
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ARG56757 anti-CCL22 / MDC antibody (Biotin) standard curve image
Sandwich ELISA: ARG56757 anti-CCL22 / MDC antibody (Biotin) as a detection antibody at 0.25 - 1.0 µg/ml combined with ARG56647 anti-CCL22 / MDC antibody as a capture antibody. Results of a typical standard run with optical density.
