ARG45336
anti-CCL19 / MIP-3 beta antibody [11B4]
anti-CCL19 / MIP-3 beta antibody [11B4] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Mouse Monoclonal antibody [11B4] recognizes CCL19 / MIP-3 beta |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 11B4 |
| 同位型 | IgG2 |
| 靶点名称 | CCL19 / MIP-3 beta |
| 抗原物种 | Human |
| 抗原 | Recombinant Human CCL19 / MIP-3 beta. |
| 偶联标记 | Un-conjugated |
| 別名 | Small-inducible cytokine A19; EBI1 ligand chemokine; CKb11; SCYA19; ELC; MIP-3b; MIP3B; C-C motif chemokine 19; Macrophage inflammatory protein 3 beta; Epstein-Barr virus-induced molecule 1 ligand chemokine; Beta-chemokine exodus-3; CK beta-11; MIP-3-beta |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein G chromatography |
| 缓冲液 | PBS |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CCL19 |
| 全名 | chemokine (C-C motif) ligand 19 |
| 背景介绍 | This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7. [provided by RefSeq, Sep 2014] |
| 生物功能 | May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 11 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG45336 anti-CCL19 / MIP-3 beta antibody [11B4] IHC-P image
Immunohistochemistry: Human placental stained with ARG45336 anti-CCL19 / MIP-3 beta antibody [11B4].
