ARG46072
anti-CCDC22 / JM1 antibody
anti-CCDC22 / JM1 antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CCDC22 / JM1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CCDC22 / JM1 |
| 抗原物种 | Human |
| 抗原 | A 18 amino acid synthetic peptide within aa. 530 - 580 of human CCDC22 / JM1. |
| 偶联标记 | Un-conjugated |
| 別名 | coiled-coil domain containing 22; CCDC22; JM1; CXorf37; JM1; Coiled-coil domain-containing protein 22 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -122°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CCDC22 |
| 全名 | coiled-coil domain containing 22 |
| 背景介绍 | This gene encodes a protein containing a coiled-coil domain. The encoded protein functions in the regulation of NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) by interacting with COMMD (copper metabolism Murr1 domain-containing) proteins. The mouse orthologous protein has been shown to bind copines, which are calcium-dependent, membrane-binding proteins that may function in calcium signaling. This human gene has been identified as a novel candidate gene for syndromic X-linked intellectual disability. [provided by RefSeq, Aug 2013] |
| 生物功能 | Component of the commander complex that is essential for endosomal recycling of transmembrane cargos; the Commander complex is composed of composed of the CCC subcomplex and the retriever subcomplex. |
| 细胞定位 | Cytoplasm; Cytoskeleton; Endosome. [UniProt] |
| 预测分子量 | 71 kDa |
| 翻译后修饰 | Phosphoprotein; Ubl conjugation. [UniProt] |
