ARG46071
anti-CCDC141 antibody
anti-CCDC141 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CCDC141 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CCDC141 |
| 抗原物种 | Human |
| 抗原 | A 18 amino acid synthetic peptide within aa. 40 - 90 of human CCDC141. |
| 偶联标记 | Un-conjugated |
| 別名 | coiled-coil domain containing 141; CCDC141; CAMDI; Coiled-coil domain-containing protein 141 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -121°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q6ZP82 Human Coiled-coil domain-containing protein 141 |
|---|---|
| 基因名称 | CCDC141 |
| 全名 | coiled-coil domain containing 141 |
| 背景介绍 | Predicted to be involved in brain development. Predicted to act upstream of or within centrosome localization and cerebral cortex radially oriented cell migration. Predicted to be located in centrosome and cytoplasm. [provided by Alliance of Genome Resources, Jul 2025] |
| 生物功能 | Plays a critical role in cortical radial and GnRH neurons migration during brain development. Regulates cortical radial migration by negatively controlling the activity of histone deacetylase 6 (HDAC6) and promotes centrosome maturation. CAMDI is required for dilation formation of cortical neurons during radial migration. Plays a critical role in learning and memory performance through regulation of AMPA-selective glutamate receptors (AMPARs) cell surface expression in competition with KIBRA. [UniProt] |
| 细胞定位 | Cytoplasm; Cytoskeleton. [UniProt] |
| 预测分子量 | 175 kDa |
| 翻译后修饰 | Phosphoprotein; Ubl conjugation. [UniProt] |
