ARG65070
anti-CCAR1 / CARP1 antibody
anti-CCAR1 / CARP1 antibody for Western blot and Mouse,Rat
Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody; Gene Regulation antibody; Metabolism antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes CCAR1 / CARP1 |
|---|---|
| 反应物种 | Ms, Rat |
| 预测物种 | Hu, Cow, Dog, Pig |
| 应用 | WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CCAR1 / CARP1 |
| 抗原物种 | Human |
| 抗原 | RYCKERPSKDKE |
| 偶联标记 | Un-conjugated |
| 別名 | Cell cycle and apoptosis regulatory protein 1; CARP-1; Cell division cycle and apoptosis regulator protein 1; Death inducer with SAP domain |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8CH18 Mouse Cell division cycle and apoptosis regulator protein 1 |
|---|---|
| 基因名称 | CCAR1 |
| 全名 | cell division cycle and apoptosis regulator 1 |
| 生物功能 | Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation (By similarity). May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation. [UniProt] |
| 研究领域 | Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody; Gene Regulation antibody; Metabolism antibody |
| 预测分子量 | 133 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG65070 anti-CCAR1 / CARP1 antibody WB image
Western blot: Rat Skeletal Muscle lysate (35 µg protein in RIPA buffer) stained with ARG65070 anti-CCAR1 / CARP1 antibody at 1 µg/ml dilution.
