ARG45209

anti-CBX2 antibody

anti-CBX2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse

概述

产品描述 Rabbit Polyclonal antibody recognizes CBX2
反应物种 Hu, Ms
应用 ICC/IF, IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 CBX2
抗原物种 Human
抗原 Recombinant protein containing to human CBX2.
偶联标记 Un-conjugated
別名 CBX2; Chromobox protein homolog 2; CDCA6; M33; SRXY5

应用说明

应用建议
应用 推荐稀释比
ICC/IF5 μg/ml
IHC-P2-5 μg/ml
WB0.25-0.5 μg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量 56 kDa

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose.
稳定剂 4% Trehalose
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 12416 Mouse CBX2

GeneID: 84733 Human CBX2

Swiss-port # P30658 Mouse Chromobox protein homolog 2

Swiss-port # Q14781 Human Chromobox protein homolog 2

基因名称 CBX2
全名 chromobox homolog 2
背景介绍 Chromobox protein homolog 2 is a protein that in humans is encoded by the CBX2 gene. This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
生物功能 Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. [UniProt]
细胞定位 Chromosome; Nucleus. [UniProt]
预测分子量 56 kDa
翻译后修饰 Isopeptide bond; Methylation; Phosphoprotein; Ubl conjugation. [UniProt]

检测图片 (4) Click the Picture to Zoom In

  • ARG45209 anti-CBX2 antibody IHC-P image

    Immunohistochemistry: Human placenta stained with ARG45209 anti-CBX2 antibody at 2 μg/ml dilution.

  • ARG45209 anti-CBX2 antibody ICC/IF image

    Immunofluorescence: A431 stained with ARG45209 anti-CBX2 antibody at 5 ug/ml dilution.

  • ARG45209 anti-CBX2 antibody WB image

    Western blot: 293T, SH-SY5Y, and MOLT-4 stained with ARG45209 anti-CBX2 antibody at 0.5 μg/ml dilution.

  • ARG45209 anti-CBX2 antibody IHC-P image

    Immunohistochemistry: Mouse testis stained with ARG45209 anti-CBX2 antibody at 2 μg/ml dilution.