ARG63841
anti-CBX1 / HP1 beta antibody
anti-CBX1 / HP1 beta antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Gene Regulation antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes CBX1 / HP1 beta |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Cow, Dog |
| 应用 | IHC-P, WB |
| 特异性 | Variants (NP_006798.1; NP_001120700.1) encode the same protein. |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CBX1 / HP1 beta |
| 抗原物种 | Human |
| 抗原 | C-QSQKTAHETDKSE |
| 偶联标记 | Un-conjugated |
| 別名 | MOD1; Chromobox protein homolog 1; HP1 beta; M31; HP1Hs-beta; Modifier 1 protein; Heterochromatin protein p25; HP1-BETA; Heterochromatin protein 1 homolog beta; CBX; HP1Hsbeta; p25beta |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] |
| 研究领域 | Gene Regulation antibody |
| 预测分子量 | 21 kDa |
| 翻译后修饰 | Not phosphorylated. Ubiquitinated. |
检测图片 (2) Click the Picture to Zoom In
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ARG63841 anti-CBX1 / HP1 beta antibody WB image
Western blot: A431 lysate (35 µg protein in RIPA buffer) stained with ARG63841 anti-CBX1 / HP1 beta antibody at 0.3 µg/ml dilution.
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ARG63841 anti-CBX1 / HP1 beta antibody IHC-P image
Immunohistochemistry: Paraffin embedded Human Placenta. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63841 anti-CBX1 / HP1 beta antibody at 2.5 µg/ml dilution followed by AP-staining.
