ARG43878
anti-CASPR2 antibody
anti-CASPR2 antibody for ELISA,Western blot and Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CASPR2 |
|---|---|
| 反应物种 | Ms, Rat |
| 预测物种 | Hu |
| 应用 | ELISA, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CASPR2 |
| 抗原物种 | Human |
| 抗原 | Human Caspr2 recombinant protein |
| 表达系统 | E.coli |
| 偶联标记 | Un-conjugated |
| Protein Full name | Contactin-associated protein-like 2 |
| 別名 | CNTNAP2; Contactin Associated Protein 2; KIAA0868; NRXN4; Contactin Associated Protein Like 2; Contactin-Associated Protein-Like 2; Cell Recognition Molecule Caspr2; Caspr2; CASPR2; Homolog Of Drosophila Neurexin IV; AUTS15; PTHSL1; CDFE |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9CPW0 Mouse Contactin-associated protein-like 2 |
|---|---|
| 基因名称 | CNTNAP2 |
| 全名 | Contactin Associated Protein 2 |
| 背景介绍 | This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2, a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and intellectual disability. |
| 生物功能 | Required for gap junction formation (Probable). Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the juxtaparanodal region of the axo-glial junction. |
| 细胞定位 | Cell junction, Cell projection, Membrane |
| 预测分子量 | 148 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Phosphoprotein |
检测图片 (1) Click the Picture to Zoom In
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ARG43878 anti-CASPR2 antibody WB image
Western blot: Rat brain and Mouse brain stained with ARG43878 anti-CASPR2 antibody at 1:5000 dilution.
