ARG46061
anti-CARD8 antibody
anti-CARD8 antibody for Western blot,ICC/IF and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CARD8 |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CARD8 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide near the C-terminus of human CARD8. |
| 偶联标记 | Un-conjugated |
| 別名 | CARD8; TUCAN; Apoptotic protein NDPP1; CARD-inhibitor of NF-kappa-B-activating ligand; NDPP1; DACAR; CARDINAL; Tumor up-regulated CARD-containing antagonist of CASP9; Caspase recruitment domain-containing protein 8; DAKAR; NDPP |
应用说明
| 应用建议 |
|
||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 47 kDa |
属性
| 纯化 | Affinity chromatography purified |
|---|---|
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9Y2G2 Human Caspase recruitment domain-containing protein 8 |
|---|---|
| 基因名称 | CARD8 |
| 全名 | caspase recruitment domain family, member 8 |
| 背景介绍 | TUCAN (Tumor Up-regulated Card-containing Antagonist of Caspase-Nine) is a CARD (Caspase-Associated Recruitment Domains) containing protein that binds and suppresses activation of pro-Caspase-9 and found to be overexpressed in some types of cancers. TUCAN binds specifically to pro-caspase-9 and interferes with its interaction with Apaf-1, thereby suppressing apoptosis signaling in the mitochondrial/cytochrome c pathway. |
| 预测分子量 | 47 kDa |
