ARG64062
anti-CARD15 / NOD2 antibody
anti-CARD15 / NOD2 antibody for Western blot and Human
Cell Biology and Cellular Response antibody; Cell Death antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes CARD15 / NOD2 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat |
| 应用 | WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CARD15 / NOD2 |
| 抗原物种 | Human |
| 抗原 | KFRFTDRERHCSPTD |
| 偶联标记 | Un-conjugated |
| 別名 | Inflammatory bowel disease protein 1; PSORAS1; BLAU; CARD15; CD; CLR16.3; NLRC2; Caspase recruitment domain-containing protein 15; IBD1; ACUG; Nucleotide-binding oligomerization domain-containing protein 2; NOD2B |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9HC29 Human Nucleotide-binding oligomerization domain-containing protein 2 |
|---|---|
| 背景介绍 | This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. [provided by RefSeq, Jul 2008] |
| 研究领域 | Cell Biology and Cellular Response antibody; Cell Death antibody |
| 预测分子量 | 115 kDa |
| 翻译后修饰 | Polyubiquitinated following MDP stimulation, leading to proteasome-mediated degradation (PubMed:23019338). |
检测图片 (1) Click the Picture to Zoom In
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ARG64062 anti-CARD15 / NOD2 antibody WB image
Western Blot: Human Peripheral Blood Mononucleocyte lysate (35 µg protein in RIPA buffer) stained with ARG64062 anti-NOD2 antibody at 0.1 µg/ml dilution.
