ARG46059
anti-CAPS2 antibody
anti-CAPS2 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CAPS2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CAPS2 |
| 抗原物种 | Human |
| 抗原 | A 19 amino acid synthetic peptide within aa. 510 - 560 of human CAPS2. |
| 偶联标记 | Un-conjugated |
| 別名 | CADPS2; Ca++-dependent secretion activator 2; CAPS2; CAPS2; KIAA1591; Calcium-dependent secretion activator 2; Calcium-dependent activator protein for secretion 2; CAPS-2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 150 kDa |
属性
| 纯化 | Affinity chromatography purified |
|---|---|
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -109°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q86UW7 Human Calcium-dependent secretion activator 2 Swiss-port # Q8BYR5 Mouse Calcium-dependent secretion activator 2 |
|---|---|
| 基因名称 | CADPS2 |
| 全名 | Ca++-dependent secretion activator 2 |
| 背景介绍 | This gene encodes a member of the calcium-dependent activator of secretion (CAPS) protein family, which are calcium binding proteins that regulate the exocytosis of synaptic and dense-core vesicles in neurons and neuroendocrine cells. Mutations in this gene may contribute to autism susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2009] |
| 生物功能 | Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates neurotrophin release from granule cells leading to regulate cell differentiation and survival during cerebellar development. May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles (By similarity). [UniProt] |
| 细胞定位 | Cell projection; Cytoplasm; Cytoplasmic vesicle; Cytoskeleton; Membrane; Synapse. [UniProt] |
| 预测分子量 | 138,145 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
