ARG64082
anti-CACNB4 antibody
anti-CACNB4 antibody for Western blot and Human
Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes CACNB4 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Dog |
| 应用 | WB |
| 特异性 | This antibody is expected to recognise all three reported isoforms (NP_001005747.1; NP_000717.2; NP_001005746.1). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CACNB4 |
| 抗原物种 | Human |
| 抗原 | C-DYPDSYQDTYKPH |
| 偶联标记 | Un-conjugated |
| 別名 | CACNLB4; EJM; EIG9; Calcium channel voltage-dependent subunit beta 4; EJM6; EJM4; Voltage-dependent L-type calcium channel subunit beta-4; EA5; CAB4 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O00305 Human Voltage-dependent L-type calcium channel subunit beta-4 |
|---|---|
| 背景介绍 | This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] |
| 研究领域 | Signaling Transduction antibody |
| 预测分子量 | 58 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG64082 anti-CACNB4 antibody WB image
Western Blot: Human Bone Marrow lysate (35 µg protein in RIPA buffer) stained with ARG64082 anti-CACNB4 antibody at 0.2 µg/ml dilution.
