ARG45193
anti-CACNA1S antibody
anti-CACNA1S antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat,Monkey
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CACNA1S |
|---|---|
| 反应物种 | Hu, Ms, Rat, Mk |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CACNA1S |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human CACNA1S. |
| 偶联标记 | Un-conjugated |
| 別名 | CACNA1S; Calcium Voltage-Gated Channel Subunit Alpha1 S; CACNL1A3; Cav1.1 ; HypoPP; Calcium Channel, Voltage-Dependent, L Type, Alpha 1S Subunit; Voltage-Dependent L-Type Calcium Channel Subunit Alpha-1S; Voltage-Gated Calcium Channel Subunit Alpha Cav1.1; HOKPP; MHS5; Calcium Channel, L Type, Alpha-1 Polypeptide, Isoform, Skeletal Muscle; Dihydropyridine-Sensitive L-Type Calcium Channel Alpha-1 Subunit; Dihydropyridine Receptor Alpha 1 Subunit; CCHL1A3; CMYO18; CMYP18; HOKPP1; DHPRM; TTPP1; CACH1; CACN1 |
应用说明
| 应用建议 |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 220 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.005% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.005% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q13698 Human Voltage-dependent L-type calcium channel subunit alpha-1S |
|---|---|
| 基因名称 | CACNA1S |
| 全名 | Calcium Voltage-Gated Channel Subunit Alpha1 S |
| 背景介绍 | This gene encodes one of the five subunits of the slowly inactivating L-type voltage-dependent calcium channel in skeletal muscle cells. Mutations in this gene have been associated with hypokalemic periodic paralysis, thyrotoxic periodic paralysis and malignant hyperthermia susceptibility. [provided by RefSeq, Jul 2008] |
| 生物功能 | Pore-forming, alpha-1S subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle via their interaction with RYR1, which triggers Ca2+ release from the sarcoplasmic reticulum and ultimately results in muscle contraction. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group.. [UniProt] |
| 细胞定位 | Membrane; Cell membrane. [UniProt] |
| 预测分子量 | 212 kDa |
| 翻译后修饰 | Disulfide bond; Glycoprotein; Phosphoprotein. [UniProt] |
检测图片 (6) Click the Picture to Zoom In
-
ARG45193 anti-CACNA1S antibody IHC-P image
Immunohistochemistry: Human skeletal muscle stained with ARG45193 anti-CACNA1S antibody at 1 μg/ml dilution.
-
ARG45193 anti-CACNA1S antibody FACS image
Flow Cytometry: U937 stained with ARG45193 anti-CACNA1S antibody at 1 µg/10^6 cells dilution.
-
ARG45193 anti-CACNA1S antibody IHC-P image
Immunohistochemistry: Rat skeletal muscle stained with ARG45193 anti-CACNA1S antibody at 1 μg/ml dilution.
-
ARG45193 anti-CACNA1S antibody WB image
Western blot: Rat skeletal muscle stained with ARG45193 anti-CACNA1S antibody at 0.5 μg/ml dilution.
-
ARG45193 anti-CACNA1S antibody WB image
Western blot: Mouse skeletal muscle stained with ARG45193 anti-CACNA1S antibody at 0.5 μg/ml dilution.
-
ARG45193 anti-CACNA1S antibody WB image
Western blot: Monkey skeletal muscle stained with ARG45193 anti-CACNA1S antibody at 0.5 μg/ml dilution.
