ARG24119
anti-CACNA1H antibody [N55/10]
anti-CACNA1H antibody [N55/10] for ICC/IF,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Mouse Monoclonal antibody [N55/10] recognizes CACNA1H |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-Fr, IHC-P, IP, WB |
| 特异性 | No cross-reactivity against Cav1.3. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | N55/10 |
| 同位型 | IgG1 |
| 靶点名称 | CACNA1H |
| 抗原物种 | Human |
| 抗原 | Human fusion protein of CACNA1H |
| 偶联标记 | Un-conjugated |
| Protein Full name | Voltage-dependent T-type calcium channel subunit alpha-1H |
| 別名 | CACNA1H; Calcium Voltage-Gated Channel Subunit Alpha1 H; Calcium Channel, Voltage-Dependent, T Type, Alpha 1H Subunit; Voltage-Dependent T-Type Calcium Channel Subunit Alpha-1H; Low-Voltage-Activated Calcium Channel Alpha1 3.2 Subunit; Voltage-Gated Calcium Channel Subunit Alpha Cav3.2; Cav3.2; Calcium Channel, Voltage-Dependent, T Type, Alpha 1Hb Subunit; Voltage Dependent T-Type Calcium Channel Alpha-1H Subunit; Low-Voltage-Activated Calcium Channel Alpha13.2 Subunit; Voltage-Gated Calcium Channel Alpha Subunit Cav3.2; Voltage-Gated Calcium Channel Alpha Subunit CavT.2; CACNA1HB; CAV3.2; HALD4; ECA6; EIG6 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 50% Glycerol and 0.09% Sodium azide |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O95180 Human Voltage-dependent T-type calcium channel subunit alpha-1H Swiss-port # Q9EQ60 Rat Voltage-dependent T-type calcium channel subunit alpha-1H |
|---|---|
| 全名 | Calcium Voltage-Gated Channel Subunit Alpha1 H |
| 背景介绍 | This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE). |
| 生物功能 | Voltage-sensitive calcium channel that gives rise to T-type calcium currents. T-type calcium channels belong to the 'low-voltage activated (LVA)' group. A particularity of this type of channel is an opening at quite negative potentials, and a voltage-dependent inactivation. |
| 细胞定位 | Cell membrane, Membrane |
| 预测分子量 | 261 kDa |
| 翻译后修饰 | Glycoprotein |
检测图片 (4) Click the Picture to Zoom In
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ARG24119 anti-CACNA1H antibody [N55/10] IHC-P image
Immunohistochemistry: Human hippocampus stained with ARG24119 anti-CACNA1H antibody [N55/10] at 1:1000 dilution.
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ARG24119 anti-CACNA1H antibody [N55/10] IHC-Fr image
Immunohistochemistry: Human hippocampus stained with ARG24119 anti-CACNA1H antibody [N55/10] at 1:1000 dilution.
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ARG24119 anti-CACNA1H antibody [N55/10] ICC/IF image
Immunofluorescence: SH-SY5Y stained with ARG24119 anti-CACNA1H antibody [N55/10] at 1:1000 dilution.
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ARG24119 anti-CACNA1H antibody [N55/10] WB image
Western blot: Rat brain stained with ARG24119 anti-CACNA1H antibody [N55/10] at 1:1000 dilution.
