ARG45539
anti-Borealin / CDCA8 antibody
anti-Borealin / CDCA8 antibody for Flow cytometry,ICC/IF,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Borealin / CDCA8 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Borealin / CDCA8 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human Borealin / CDCA8. |
| 偶联标记 | Un-conjugated |
| 別名 | CDCA8; Cell Division Cycle Associated 8; Borealin; MESRGP; DasraB; BOR; Pluripotent Embryonic Stem Cell-Related Gene 3 Protein; Cell Division Cycle-Associated Protein 8; FLJ12042; HDasra-B; Dasra-B; Dasra B; PESCRG3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 35 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CDCA8 |
| 全名 | Cell Division Cycle Associated 8 |
| 背景介绍 | This gene encodes a component of the chromosomal passenger complex. This complex is an essential regulator of mitosis and cell division. This protein is cell-cycle regulated and is required for chromatin-induced microtubule stabilization and spindle formation. Alternate splicing results in multiple transcript variants. Pseudgenes of this gene are found on chromosomes 7, 8 and 16. [provided by RefSeq, Apr 2013] |
| 生物功能 | Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment. [UniProt] |
| 细胞定位 | Centromere; Chromosome; Cytoplasm; Cytoskeleton; Nucleus. [UniProt] |
| 预测分子量 | 31 kDa |
| 翻译后修饰 | Isopeptide bond; Phosphoprotein; Ubl conjugation. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG45539 anti-Borealin / CDCA8 antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG45539 anti-Borealin / CDCA8 antibody at 5 μg/ml dilution.
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ARG45539 anti-Borealin / CDCA8 antibody WB image
Western blot: K562 stained with ARG45539 anti-Borealin / CDCA8 antibody at 0.5 μg/ml dilution.
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ARG45539 anti-Borealin / CDCA8 antibody FACS image
Flow Cytometry: K562 stained with ARG45539 anti-Borealin / CDCA8 antibody at 1 µg/10^6 cells dilution.
