ARG43925
anti-Bcl 11B / Ctip2 antibody
anti-Bcl 11B / Ctip2 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Bcl 11B / Ctip2 |
|---|---|
| 反应物种 | Hu, Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Bcl 11B / Ctip2 |
| 抗原物种 | Human |
| 抗原 | Human Bcl 11B / Ctip2 recombinant protein |
| 表达系统 | E.coli |
| 偶联标记 | Un-conjugated |
| Protein Full name | B-cell lymphoma/leukemia 11B |
| 別名 | CL11B; BCL11 Transcription Factor B; CTIP2; BAF Chromatin Remodeling Complex Subunit BCL11B; HRIT1-Alpha; SMARCM2; CTIP-2; Radiation-Induced Tumor Suppressor Gene 1 Protein; B-Cell CLL/Lymphoma 11B (Zinc Finger Protein); BCL11B, BAF Complex Component; COUP-TF-Interacting Protein 2; B-Cell Lymphoma/Leukemia 11B; B Cell CLL/Lymphoma 11B; ZNF856B; BCL-11B; HRit1; RIT1; B-Cell CLL/Lymphoma 11B/T-Cell Receptor Delta Constant Region Fusion Protein; Zinc Finger Protein HRit1 Alpha; B-Cell Lymphoma/Leukaemia 11B; B-Cell CLL/Lymphoma 11B; BCL11B/TRDC Fusion; ATL1-Alpha; ATL1-Delta; ATL1-Gamma; ATL1-Beta; IDDFSTA; IMD49; ATL1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | BCL11B |
| 全名 | BCL11 Transcription Factor B |
| 背景介绍 | This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| 生物功能 | Key regulator of both differentiation and survival of T-lymphocytes during thymocyte development in mammals. Essential in controlling the responsiveness of hematopoietic stem cells to chemotactic signals by modulating the expression of the receptors CCR7 and CCR9, which direct the movement of progenitor cells from the bone marrow to the thymus. |
| 细胞定位 | Nucleus |
| 预测分子量 | 96 kDa |
| 翻译后修饰 | Acetylation, Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugation |
检测图片 (6) Click the Picture to Zoom In
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ARG43925 anti-Bcl 11B / Ctip2 antibody IHC-P image
Immunohistochemistry: Human breast cancer stained with ARG43925 anti-Bcl 11B / Ctip2 antibody at 2 μg/ml dilution.
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ARG43925 anti-Bcl 11B / Ctip2 antibody WB image
Western blot: MOLT-4 stained with ARG43925 anti-Bcl 11B / Ctip2 antibody at 0.5 μg/mL dilution.
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ARG43925 anti-Bcl 11B / Ctip2 antibody FACS image
Flow Cytometry: C6 cells stained with ARG43925 anti-Bcl 11B / Ctip2 antibody (blue) at 1 μg/1x10^6 cells dilution.
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ARG43925 anti-Bcl 11B / Ctip2 antibody ICC/IF image
Immunofluorescence: U2OS cells stained with ARG43925 anti-Bcl 11B / Ctip2 antibody at 5 μg/ml dilution.
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ARG43925 anti-Bcl 11B / Ctip2 antibody IHC-P image
Immunohistochemistry: Human lymph node metastasis carcinoma stained with ARG43925 anti-Bcl 11B / Ctip2 antibody at 2 μg/ml dilution.
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ARG43925 anti-Bcl 11B / Ctip2 antibody IHC-P image
Immunohistochemistry: Human placenta stained with ARG43925 anti-Bcl 11B / Ctip2 antibody at 2 μg/ml dilution.
