ARG63187
anti-Bak antibody
anti-Bak antibody for Western blot and Human
Cell Biology and Cellular Response antibody; Cell Death antibody; Pro-apoptotic Bcl2 protein antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes Bak |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Pig |
| 应用 | WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Bak |
| 抗原物种 | Human |
| 抗原 | ASGQGPGPPRQE-C |
| 偶联标记 | Un-conjugated |
| 別名 | Apoptosis regulator BAK; BCL2L7; Bcl-2-like protein 7; CDN1; Bcl2-L-7; Bcl-2 homologous antagonist/killer; BAK-LIKE; BAK |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q16611 Human Bcl-2 homologous antagonist/killer |
|---|---|
| 背景介绍 | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008] |
| 研究领域 | Cell Biology and Cellular Response antibody; Cell Death antibody; Pro-apoptotic Bcl2 protein antibody |
| 预测分子量 | 23 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG63187 anti-Bak antibody WB image
Western blot: A431 lysate (RIPA buffer, 30µg total protein per lane) stained with ARG63187 anti-Bak antibody at 0.5 µg/ml dilution.
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ARG63187 anti-Bak antibody WB image
Western blot: 35 µg of Human adrenal gland lysate (in RIPA buffer) stained with ARG63187 anti-Bak antibody at 2 µg/ml dilution and incubated at RT for 1 hour.
