概述

产品描述	Rabbit Polyclonal antibody recognizes BSND
反应物种	Hu, Ms, Rat
应用	WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	BSND
抗原物种	Human
抗原	Recombinant protein of Human BSND
偶联标记	Un-conjugated
別名	BART; DFNB73; Barttin

应用说明

应用建议	应用 推荐稀释比 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	Rat intestine

属性

形式	Liquid
纯化	Affinity purification with immunogen.
缓冲液	PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 140475 Mouse BSND GeneID: 192675 Rat BSND GeneID: 7809 Human BSND Swiss-port # Q8R2H3 Rat Barttin Swiss-port # Q8VIM4 Mouse Barttin Swiss-port # Q8WZ55 Human Barttin More
基因名称	BSND
全名	barttin CLCNK-type chloride channel accessory beta subunit
背景介绍	This gene encodes an essential beta subunit for CLC chloride channels. These heteromeric channels localize to basolateral membranes of renal tubules and of potassium-secreting epithelia of the inner ear. Mutations in this gene have been associated with Bartter syndrome with sensorineural deafness. [provided by RefSeq, Jul 2008]
生物功能	Functions as a beta-subunit for CLCNKA and CLCNKB chloride channels. In the kidney CLCNK/BSND heteromers mediate chloride reabsorption by facilitating its basolateral efflux. In the stria, CLCNK/BSND channels drive potassium secretion by recycling chloride for the basolateral SLC12A2 cotransporter. [UniProt]
预测分子量	35 kDa
翻译后修饰	Palmitoylation is necessary for activation of plasma membrane-inserted CLC-K/barttin channels.

检测图片 (1) Click the Picture to Zoom In