ARG54459
anti-BRD2 antibody
anti-BRD2 antibody for Western blot and Human
Cell Biology and Cellular Response antibody; Gene Regulation antibody; Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes BRD2 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 特异性 | This antibody reacts with human BRD2. The specific epitope is in the region between aa 550 and 600 of human BRD2. Based on 100% sequence identity, this antibody is predicted to react with Bovine, Rhesus Monkey, Gorilla, White-tufted-ear marmoset, Crab-eating macaque and Northern white-cheeked gibbon. |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | BRD2 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide representing a portion of the protein between the putative nuclear localization signal and the ET domain |
| 偶联标记 | Un-conjugated |
| 別名 | O27.1.1; FSH; RING3; D6S113E; FSRG1; Really interesting new gene 3 protein; NAT; Bromodomain-containing protein 2; RNF3 |
应用说明
| 预测反应性说明 | Bovine, Rhesus Monkey, Gorilla, White-tufted-ear marmoset, Crab-eating macaque and Northern white-cheeked gibbon. | ||||
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| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | HeLa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity-purified with an epitope specific to BRD2 immobilized on solid support. |
| 缓冲液 | Tris-citrate/phosphate (pH 7-8) and 0.09% Sodium azide |
| 抗菌剂 | 0.09% Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | BRD2 |
| 全名 | bromodomain containing 2 |
| 背景介绍 | BRD2 (bromodomain-containing 2) is a nuclear mitogen-activated kinase that plays a role in transcription of cell-cycle-regulated genes by functioning as an adapter protein that recruits E2F and chromatin remodeling factors to E2F response elements. |
| 生物功能 | May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly. [UniProt] |
| 研究领域 | Cell Biology and Cellular Response antibody; Gene Regulation antibody; Signaling Transduction antibody |
| 预测分子量 | 88 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG54459 anti-BRD2 antibody WB image
Western Blot: 10ug of HeLa cells untreated (-) or treated (+) with calf intestinal phosphatase stained with ARG54459 anti-BRD2 antibody at 0.05ug/ml dilution.
