概述

产品描述	Rabbit Polyclonal antibody recognizes BNIP1
反应物种	Hu, Ms, Rat
应用	IHC-P, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	BNIP1
抗原物种	Human
抗原	Synthetic peptide of Human BNIP1.
偶联标记	Un-conjugated
別名	Transformation-related gene 8 protein; BCL2/adenovirus E1B 19 kDa protein-interacting protein 1; TRG-8; Vesicle transport protein SEC20; SEC20; NIP1

应用说明

应用建议	应用 推荐稀释比 IHC-P 1:50 - 1:200 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	Jurkat
实际分子量	~ 26 kDa

属性

形式	Liquid
纯化	Affinity purified.
缓冲液	PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 140932 Rat BNIP1 GeneID: 224630 Mouse BNIP1 GeneID: 662 Human BNIP1 Swiss-port # Q12981 Human Vesicle transport protein SEC20 Swiss-port # Q6QD59 Mouse Vesicle transport protein SEC20 Swiss-port # Q8VHI8 Rat Vesicle transport protein SEC20 More
基因名称	BNIP1
全名	BCL2/adenovirus E1B 19kDa interacting protein 1
背景介绍	This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. In addition, this protein is involved in vesicle transport into the endoplasmic reticulum. Alternative splicing of this gene results in four protein products with identical N- and C-termini. [provided by RefSeq, Mar 2011]
生物功能	SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Required for maintenance of ER network. Implicated in the suppression of cell death. May be involved in mitochondrial autophagy. [UniProt]
细胞定位	Mitochondrion. Endoplasmic reticulum membrane; Single-pass type IV membrane protein. [UniProt]
预测分子量	26 kDa
翻译后修饰	'Lys-63'-linked polyubiquitination by RNF185 allows recruiting of autophagy receptor SQSTM1, which simultaneously binds both ubiquitin and LC3 to link ubiquitination and autophagy. [UniProt]

检测图片 (1) Click the Picture to Zoom In