ARG44564
anti-BMP15 antibody
anti-BMP15 antibody for ICC/IF,Western blot and Human,Mouse
Premature ovarian failure. [UniProt]
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes BMP15 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | BMP15 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human BMP15 (a.a. 30-80). |
| 偶联标记 | Un-conjugated |
| 別名 | BMP15; Bone Morphogenetic Protein 15; GDF9B; Growth/Differentiation Factor 9B; BMP-15; GDF-9B; ODG2; POF4 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography using the peptide immobilized |
| 缓冲液 | PBS with 0.02% sodium azide. |
| 抗菌剂 | 0.02% sodium azide. |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | BMP15 |
| 全名 | Bone Morphogenetic Protein 15 |
| 背景介绍 | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 (GDF9). This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure. [provided by RefSeq, Aug 2016] |
| 生物功能 | May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 研究领域 | Premature ovarian failure. [UniProt] |
| 预测分子量 | 45 kDa |
| 翻译后修饰 | Secreted. [UniProt] |
