ARG44558
anti-BMP15 antibody
anti-BMP15 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Premature ovarian failure. [UniProt]
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes BMP15 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | BMP15 |
| 抗原物种 | Human |
| 抗原 | A synthetic peptide corresponding to a sequence at the C-terminus of human BMP15 |
| 偶联标记 | Un-conjugated |
| 別名 | BMP15; Bone Morphogenetic Protein 15; GDF9B; Growth/Differentiation Factor 9B; BMP-15; GDF-9B; ODG2; POF4 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | BMP15 |
| 全名 | Bone Morphogenetic Protein 15 |
| 背景介绍 | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 (GDF9). This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure. [provided by RefSeq, Aug 2016] |
| 生物功能 | May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 研究领域 | Premature ovarian failure. [UniProt] |
| 预测分子量 | 45 kDa |
| 翻译后修饰 | Secreted. [UniProt] |
检测图片 (6) Click the Picture to Zoom In
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ARG44558 anti-BMP15 antibody IHC-P image
Immunohistochemistry: Human intestinal stained cancer with ARG44558 anti-BMP15 antibody at 1 μg/ml dilution.
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ARG44558 anti-BMP15 antibody WB image
Western blot: Caco-2 stained with ARG44558 anti-BMP15 antibody at 0.5 μg/ml dilution.
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ARG44558 anti-BMP15 antibody WB image
Western blot: Rat lung stained with ARG44558 anti-BMP15 antibody at 0.5 μg/ml dilution.
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ARG44558 anti-BMP15 antibody WB image
Western blot: Mouse lung stained with ARG44558 anti-BMP15 antibody at 0.5 μg/ml dilution.
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ARG44558 anti-BMP15 antibody IHC-P image
Immunohistochemistry: Human lung cancer stained with ARG44558 anti-BMP15 antibody at 1 μg/ml dilution.
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ARG44558 anti-BMP15 antibody WB image
Western blot: Human placenta stained with ARG44558 anti-BMP15 antibody at 0.5 μg/ml dilution.
