ARG42102
anti-BMP1 antibody
anti-BMP1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Goat Polyclonal antibody recognizes BMP1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 预测物种 | Cow, Dog, Pig |
| 应用 | IHC-P, WB |
| 特异性 | This antibody is expected to recognize both reported isoforms (NP_001190.1; NP_006120.1). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | BMP1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the internal region of Human BMP1. (C-DTIVPKYEVNGVK) (NP_001190.1; NP_006120.1) |
| 偶联标记 | Un-conjugated |
| 別名 | OI13; Procollagen C-proteinase; PCP; PCOLC; PCP2; BMP-1; Bone morphogenetic protein 1; Mammalian tolloid protein; TLD; EC 3.4.24.19; mTld |
应用说明
| 应用建议 |
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| 应用说明 | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 实际分子量 | ~ 110 kDa (Human) |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | BMP1 |
| 全名 | bone morphogenetic protein 1 |
| 背景介绍 | This gene encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, this gene encodes a protein that is not closely related to other known growth factors. This gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region. [provided by RefSeq, Aug 2008] |
| 生物功能 | Cleaves the C-terminal propeptides of procollagen I, II and III. Induces cartilage and bone formation. May participate in dorsoventral patterning during early development by cleaving chordin (CHRD). Responsible for the proteolytic activation of lysyl oxidase LOX. [UniProt] |
| 细胞定位 | Golgi apparatus, trans-Golgi network. Secreted, extracellular space, extracellular matrix. Note=Co-localizes with POSTN in the Golgi. [UniProt] |
| 预测分子量 | 111 kDa (Human) |
| 翻译后修饰 | Proteolytically activated in the trans-Golgi network by furin-like/paired basic proprotein convertases, cleavage is not required for secretion. [UniProt] |
检测图片 (5) Click the Picture to Zoom In
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ARG42102 anti-BMP1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human cortex tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG42102 anti-BMP1 antibody at 5 µg/ml dilution.
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ARG42102 anti-BMP1 antibody WB image
Western blot: 35 µg of Human heart and Human kidney lysates (in RIPA buffer) stained with ARG42102 anti-BMP1 antibody at 1 µg/ml dilution and incubated at RT for 1 hour.
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ARG42102 anti-BMP1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human placenta tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG42102 anti-BMP1 antibody at 5 µg/ml dilution.
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ARG42102 anti-BMP1 antibody WB image
Western blot: 35 µg of Rat heart lysate (in RIPA buffer) stained with ARG42102 anti-BMP1 antibody at 2 µg/ml dilution and incubated at RT for 1 hour.
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ARG42102 anti-BMP1 antibody WB image
Western blot: 35 µg of NIH/3T3 cell lysate (in RIPA buffer) stained with ARG42102 anti-BMP1 antibody at 2 µg/ml dilution and incubated at RT for 1 hour.
