ARG42078
anti-BMP1 antibody
anti-BMP1 antibody for ICC/IF,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes BMP1 |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | BMP1 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human BMP1. |
| 偶联标记 | Un-conjugated |
| 別名 | OI13; Procollagen C-proteinase; PCP; PCOLC; PCP2; BMP-1; Bone morphogenetic protein 1; Mammalian tolloid protein; TLD; EC 3.4.24.19; mTld |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | U-251 MG | ||||||
| 实际分子量 | ~ 95 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide. |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | BMP1 |
| 全名 | bone morphogenetic protein 1 |
| 背景介绍 | This gene encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, this gene encodes a protein that is not closely related to other known growth factors. This gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region. [provided by RefSeq, Aug 2008] |
| 生物功能 | Cleaves the C-terminal propeptides of procollagen I, II and III. Induces cartilage and bone formation. May participate in dorsoventral patterning during early development by cleaving chordin (CHRD). Responsible for the proteolytic activation of lysyl oxidase LOX. [UniProt] |
| 细胞定位 | Golgi apparatus, trans-Golgi network. Secreted, extracellular space, extracellular matrix. Note=Co-localizes with POSTN in the Golgi. [UniProt] |
| 预测分子量 | 111 kDa |
| 翻译后修饰 | Proteolytically activated in the trans-Golgi network by furin-like/paired basic proprotein convertases, cleavage is not required for secretion. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG42078 anti-BMP1 antibody ICC/IF image
Immunofluorescence: 4% Paraformaldehyde-fixed, 0.1% Triton X-100 permeabilized A549 cells stained with ARG42078 anti-BMP1 antibody (green) at 1:25 dilution. Dylight® 554 Phalloidin (red) for cytoplasmic actin staining. DAPI (blue) for nuclear staining.
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ARG42078 anti-BMP1 antibody WB image
Western blot: 20 µg of U-251 MG whole cell lysate stained with ARG42078 anti-BMP1 antibody at 1:2000 dilution.
