ARG63654
anti-BIRC7 / LIVIN antibody
anti-BIRC7 / LIVIN antibody for Western blot and Human
Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes BIRC7 / LIVIN |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 特异性 | This antibody is expected to recognise both reported isoforms (as represented by NP_647478.1 and NP_071444.1) |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | BIRC7 / LIVIN |
| 抗原物种 | Human |
| 抗原 | C-RAPVRSRVRT |
| 偶联标记 | Un-conjugated |
| 別名 | p30-Livin; ML-IAP; Baculoviral IAP repeat-containing protein 7; EC 6.3.2.-; RNF50; Melanoma inhibitor of apoptosis protein; Livin; tLivin; Kidney inhibitor of apoptosis protein; Truncated livin; RING finger protein 50; KIAP; MLIAP; LIVIN |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q96CA5 Human Baculoviral IAP repeat-containing protein 7 |
|---|---|
| 背景介绍 | The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide. [provided by RefSeq, Jul 2008] |
| 研究领域 | Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody |
| 预测分子量 | 33 kDa |
| 翻译后修饰 | Autoubiquitinated and undergoes proteasome-mediated degradation. The truncated protein (tLivin) not only loses its anti-apoptotic effect but also acquires a pro-apoptotic effect. |
检测图片 (2) Click the Picture to Zoom In
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ARG63654 anti-BIRC7 / LIVIN antibody WB image
Western blot: MOLT4 lysate (35 µg protein in RIPA buffer) stained with ARG63654 anti-BIRC7 / LIVIN antibody at 0.3 µg/ml dilution.
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ARG63654 anti-BIRC7 / LIVIN antibody WB image
Western blot: Daudi (A), Jurkat (B) and K562 (C) lysates (35 µg protein in RIPA buffer) stained with ARG63654 anti-BIRC7 / LIVIN antibody at 0.5 µg/ml dilution.
