ARG66939
anti-BCMA antibody [SQab22269]
anti-BCMA antibody [SQab22269] for IHC-Formalin-fixed paraffin-embedded sections and Human
Cancer antibody; Immune System antibody; Signaling Transduction antibody
概述
| 产品描述 | Recombinant Rabbit Monoclonal antibody [SQab22269] recognizes BCMA |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | SQab22269 |
| 同位型 | IgG |
| 靶点名称 | BCMA |
| 抗原物种 | Human |
| 抗原 | Full length protein corresponding to Human BCMA. |
| 偶联标记 | Un-conjugated |
| Protein Full name | Tumor necrosis factor receptor superfamily member 17 |
| 別名 | BCM; BCMA; CD269; CD antigen CD269; Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; TNFRSF13A |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0). Incubate the samples at RT (18-25°C) for 30 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 阳性对照 | Human DBLCL |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05%BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q02223 Human Tumor necrosis factor receptor superfamily member 17 |
|---|---|
| 基因名称 | TNFRSF17 |
| 全名 | tumor necrosis factor receptor superfamily, member 17 |
| 背景介绍 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008] |
| 生物功能 | Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. [UniProt] |
| 研究领域 | Cancer antibody; Immune System antibody; Signaling Transduction antibody |
| 预测分子量 | 20 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG66939 anti-BCMA antibody [SQab22269] IHC-P image
Immunohistochemistry: Formalin/PFA-fixed and paraffin-embedded sections of Human DBLCL stained with ARG66939 anti-BCMA antibody [SQab22269]. Antigen Retrieval: Heat tissue section in Tris-EDTA buffer (pH 9.0).
