ARG43072
anti-BCKDK antibody
anti-BCKDK antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes BCKDK |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | BCKDK |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human BCKDK. |
| 偶联标记 | Un-conjugated |
| 別名 | BCKD-kinase; [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial; BDK; Branched-chain alpha-ketoacid dehydrogenase kinase; BCKDHKIN; BCKDKD; EC 2.7.11.4 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | HeLa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | 50 mM Tris-Glycine (pH 7.4), 150 mM NaCl, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 浓度 | Batch dependent |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | BCKDK |
| 全名 | branched chain ketoacid dehydrogenase kinase |
| 背景介绍 | The branched-chain alpha-ketoacid dehydrogenase complex (BCKD) is an important regulator of the valine, leucine, and isoleucine catabolic pathways. The protein encoded by this gene is found in the mitochondrion, where it phosphorylates and inactivates BCKD. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012] |
| 生物功能 | Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex. [UniProt] |
| 细胞定位 | Mitochondrion matrix. Mitochondrion. [UniProt] |
| 预测分子量 | 46 kDa |
| 翻译后修饰 | Autophosphorylated. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG43072 anti-BCKDK antibody WB image
Western blot: HeLa cell lysate stained with ARG43072 anti-BCKDK antibody at 1:1000 dilution.
