ARG59956
anti-BCAS3 antibody
anti-BCAS3 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes BCAS3 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | BCAS3 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 674-913 of Human BCAS3 (NP_060149.3). |
| 偶联标记 | Un-conjugated |
| 別名 | Breast carcinoma-amplified sequence 3; GAOB1; MAAB |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 阳性对照 | Rat brain and HeLa | ||||||||||
| 实际分子量 | 115 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8CCN5 Mouse Breast carcinoma-amplified sequence 3 homolog Swiss-port # Q9H6U6 Human Breast carcinoma-amplified sequence 3 |
|---|---|
| 基因名称 | BCAS3 |
| 全名 | breast carcinoma amplified sequence 3 |
| 生物功能 | Plays a role in angiogenesis. Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge. Promotes filipodia formation (By similarity). Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase activity. Binds to chromatin. [UniProt] |
| 细胞定位 | Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Note=Localizes in the cytoplasm in stationary cells. Translocates from the cytoplasm to the leading edge in motile cells. Colocalizes with microtubules and intermediate filaments in both stationary and motile cells (By similarity). Associates with chromatin. Recruited to estrogen receptor-induced promoters in a PELP1-dependent manner. [UniProt] |
| 预测分子量 | 101 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG59956 anti-BCAS3 antibody ICC/IF image
Immunofluorescence: A549 cells stained with ARG59956 anti-BCAS3 antibody.
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ARG59956 anti-BCAS3 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human kidney cancer stained with ARG59956 anti-BCAS3 antibody at 1:100 dilution.
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ARG59956 anti-BCAS3 antibody WB image
Western blot: 25 µg of Rat brain and HeLa cell lysates stained with ARG59956 anti-BCAS3 antibody at 1:1000 dilution.
